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Diabetic Men Have Lower Risk of Prostate Cancer

As epidemiologic evidence suggests diabetic men have a slightly lower prostate cancer risk than non-diabetic men. Seattle researchers examined this association in a prospective cohort study of 35 239 men, 50–76 years old, in Washington State who completed a baseline questionnaire between 2000 and 2002. Incident prostate cancers as of 31 December 2004 were identified through the SEER registry.

They found that diabetic men had a slightly lower risk of prostate cancer than non-diabetic men (hazard ratio (HR) 0.83). Insulin users overall and insulin users with diabetic complications had decreased risks, compared to non-diabetic men (HR 0.49) and (HR 0.36), respectively. Oral medication use for diabetes was not associated with prostate cancer. Insulin is likely a marker of severity of diabetes.

The researchers concluded: “Future studies of this association should consider diabetes type, treatment, severity, complications and biomarkers”

An interesting association that might be somewhat reassuring for diabetic men.

Diabetes and the risk of prostate cancer: the role of diabetes treatment and complications, C M Velicer, S Dublin and E White. Category Y. Male Genital System, Breast, U. Urinary System.. Posted on Global Family Doctor 22 March 2007

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