Individuals with diabetic foot ulcers were shown to be at greater risk of premature death from vascular and nonvascular causes than those without ulcers, in a recent study. Researchers obtained data for patients who attended a secondary care diabetic foot clinic or a general diabetes clinic between 2009 and 2010. The control group consisted of a clinic cohort of patients with diabetes and no history of diabetic foot ulceration (DFU). Overall, researchers recorded 145 events of all-cause mortality and 27 events of cardiovascular mortality among 869 patients with diabetes during a median follow-up of 3.6 years. After adjustment for potential confounders, DFU was associated with both cardiovascular disease (hazard ratio, 2.53; 95% confidence interval, 0.98-6.49; P = .05) and all-cause mortality (hazard ratio, 3.98; 95% confidence interval, 2.55-6.21; P < .001). -- Brownrigg JRW. J Vasc Surg. 2014;doi:10.1016/j.jvs.2014.04.052.