Wednesday , May 23 2018
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Metformin Therapy Center

Metformin for Obese Children

Metformin was linked to reduced food intake, decreased hunger ratings, and increased fullness ratings… For obese hyperinsulinemic children, metformin seems to decrease perceived hunger and increase perceived fullness, according to a published study. Mopelola A. Adeyemo, M.P.H., from the National Institutes of Health in Bethesda, Md., and colleagues examined the …

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FDA Approves Xigduo XR, a New Dapagliflozin-Metformin Combination

The once-daily oral tablet is the first in the U.S. to combine the SGLT-2 inhibitor dapagliflozin with the biguanide extended-release (XR) metformin hydrochloride.. The US Food and Drug Administration (FDA) has approved a once-daily combination of dapagliflozin and metformin hydrochloride extended-release (Xigduo XR, AstraZeneca) for the treatment of adults with …

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Metformin Is Best Initial Oral Drug for Lowering Glucose Levels in Diabetes Patients

Metformin, sulfonylureas, thiazolidinedione, and DPP-4 inhibitors were compared to evaluate the effects on the time to subsequent treatment… There are many classes of oral drugs used for diabetes therapy, but there is a lack of evidence as to which drug is best for use as initial therapy. Most patients diagnosed …

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SGLT2 Inhibitors as Add-On for Poorly Controlled Patients on DPP-4s and Metformin

As the diabetes epidemic continues to grow, practitioners are increasingly searching for medication solutions that can help patients to better manage their diabetes. This month, we have a recent slides series from the ADA showing the positive effects of adding-on SGLT-2 inhibitors to the medication regimen of patients on DPP-4’s …

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