Metformin Therapy Center

Should metformin or glyburide, or a combination of both drugs, be the first-line treatment for gestational diabetes?

Pioglitazone in people with insulin resistance, prediabetes or diabetes is associated with a decreased risk for major adverse cardiovascular events, study data shows.

FDA label update will increase drug use in persons with historical contraindications or precautions.

Meta-analysis found metformin therapy was associated with decreased risk for colorectal adenomas and colorectal cancer among T2 patients.

Many of our patients have intolerable GI side effects from metformin. We use ER to try to decrease these, but that doesn’t always work. If they have these symptoms, I recommend they take it slow and take it after they eat. If they still have problems, I recommend they break the tablet to 250mg, even though the label may say one shouldn’t break the tablet.

Scientists believe drug commonly prescribed for T2 could be routinely taken by T1 patients.

Metformin use has been associated with significant disturbances in acid-base balance.

In a controlled trial, 600 overweight and obese people with prediabetes were given metformin.

Is once-daily delayed release metformin better than the other forms of metformin?

The diabetes drug may have a beneficial effect on neurodegenerative diseases.