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Meglitinides

Practical Diabetes Care, 3rd Ed., Excerpt #8: Pharmacological Treatment of Hyperglycemia Part 1 of 2

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David Levy, MD, FRCP Introduction The pharmacological management of blood glucose in type 2 diabetes remains the most contentious area of diabetes management, and although until relatively recently in the USA the only agents to treat blood glucose were insulin and sulphonylureas, this limited repertoire in no way inhibited the controversy, ...

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Joslin’s Diabetes Deskbook, Updated 2nd Ed., Excerpt #51: Pharmacotherapy of Type 2 Diabetes, Part 10

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Richard S. Beaser, MD Medications that Increase Insulin Secretion: SULFONYLUREAS CLASS SUMMARY: Action: Insulin secretagogues. Initial effects are to increase insulin secretory capacity. With establishment of long-term glucose control, this increase may not persist and other extrapancreatic effects, either direct or indirect, may also occur. Required for efficacy: Some remaining ...

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Joslin’s Diabetes Deskbook, Updated 2nd Ed., Excerpt #43: Pharmacotherapy of Type 2 Diabetes, Part 2

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Richard S. Beaser, MD This week’s excerpt covers the following topics: The mechanism of action for antidiabetes medications Which medications improve insulin action Which meds slow gastric absorption Which meds increase insulin secretion Which meds increase the effect of incretins How to compare diabetes meds  

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