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Insulin Therapy Center

Insulin Therapy for Diabetes: Diabetes in Control answers key questions about the uses and challenges of insulin in diabetes management, including:
– How insulin is used to treat diabetes
– How/when a healthcare professional should consider insulin therapy for diabetes patients
– What a healthcare professional needs to know about making insulin therapy safe and effective

Blocking a Genetic Variant Associated with Type 2 Diabetes May Improve Insulin Secretion

Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …

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Adding an SGLT2 to Insulin Improved Control

Adding an SGLT2 inhibitor to multiple daily doses of insulin improved glycemic control, benefited weight loss, lowered insulin doses, and no increase in hypoglycemia was seen…   Some patients with inadequately controlled type 2 diabetes still do not achieve glycemic control with multiple daily doses of insulin. Empagliflozin is a …

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New GLP-1 Receptor Agonist as an Alternative to Insulin Glargine?

Dulaglutide shows efficacy in diabetes patients with poor glycemic control already taking multiple oral medications…. Patients with uncontrolled diabetes already taking multiple oral agents often require insulin therapy for better glycemic control but insulin therapy is associated with hypoglycemia and weight gain. Dulaglutide, approved by the FDA in September 2014, …

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Post-surgery Complications More Likely with Insulin-dependent Diabetes

Insulin-dependent diabetes patients were at an increased risk of post-surgery complications following lumbar fusion including death, sepsis, wound infection and 30-day readmission…. Patients with insulin-dependent diabetes mellitus (IDDM) have an increased risk of a number of postoperative complications after lumbar fusion compared with those who have noninsulin-dependent diabetes mellitus (NIDDM) …

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