Insulin Therapy Center

Glargine 300 more effective than glargine 100 currently available… Two single-dose studies were conducted in Japan and Europe to compare the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of new insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) in people with type 1 diabetes mellitus. In two double-blind, randomized, crossover …

Can metformin reduce the risk of cancer for those with type 2 diabetes?… In previous studies, metformin has been shown to decrease the risk of cancer in type 2 diabetes. A recent meta-analysis showed a 34% reduction in the incidence of any cancer and a 33% reduction in cancer mortality; …

The women also experienced reduced beta cell function…. Researchers from the University of Southern California, Los Angeles, assessed associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM …

  The t:flex Pump is designed for patients who require more than 100 units of U-100 insulin per day, such as teenagers with type 1 diabetes and many people with type 2 diabetes. The pump offers the benefits of pump therapy without the frequent reservoir changes required by 200- and …

According to a new study, about 1/3 of people with type 1 diabetes produce insulin, as measured by C-peptide, even upward of 40 years from initial diagnosis… The findings shed new light on the long-accepted belief that patients with type 1 diabetes lose all ability to produce any insulin. The …

Elevated fasting insulin levels in children aged 3 to 6 years may help predict which children will develop type 2 diabetes as adults… Although researchers did not find the same association for older children and adolescents, they did find an association between body mass index (BMI) in peripubertal years and …

  Animas, a division of Johnson & Johnson, has finally won FDA approval for its Vibe insulin pump and continuous glucose monitoring system. The pump is the first to pair with Dexcom’s G4 PLATINUM continuous glucose monitor that samples interstitial fluid every five minutes and provides a trending chart of …

Ricardo, a 35-year-old man newly diagnosed with type 1 diabetes, was hospitalized for diabetic ketoacidosis (DKA). Once he was stabilized, he wanted to go home. He refused to learn how to self-administer insulin. However, he was told he would not be discharged until he self-administered insulin, at least one time. I …

About 11,000 patients using both insulin and sulfonylurea were evaluated… Ulrik M. Mogensen, MD, of the department of cardiology at University Hospital Rigshospitalet in Denmark, and colleagues evaluated patients receiving sulfonylurea with insulin and 16,910 patients receiving metformin with insulin to determine the differences in outcomes of treatment combinations. Outcome …

Improved glycemic control can reduce A1c, medical costs and complications… According to a new study, early introduction of insulin could save money, help more patients reach A1c goals and decrease diabetes-related complications and mortality. Currently, insulin therapy for persons with type 2 diabetes is traditionally added to an anti-hyperglycemic regimen …