Insulin Therapy Center

About 11,000 patients using both insulin and sulfonylurea were evaluated… Ulrik M. Mogensen, MD, of the department of cardiology at University Hospital Rigshospitalet in Denmark, and colleagues evaluated patients receiving sulfonylurea with insulin and 16,910 patients receiving metformin with insulin to determine the differences in outcomes of treatment combinations. Outcome …

Improved glycemic control can reduce A1c, medical costs and complications… According to a new study, early introduction of insulin could save money, help more patients reach A1c goals and decrease diabetes-related complications and mortality. Currently, insulin therapy for persons with type 2 diabetes is traditionally added to an anti-hyperglycemic regimen …

Increased risk seen in both type 1 and type 2 diabetes patients treated with insulin. Insulin-treated patients with diabetes who experience hypoglycemia are also more likely to experience cardiovascular events and die from any cause, according to the current research. The link between hypoglycemia and CV outcomes and death remains …

Recently, a patient of mine called about her post-meal glucose levels which were increasing.

An 83-year-old woman who lived alone and was very active in her community was having wide swings in her glucose levels. She reported sometimes waking up hours after dinner with her head in her dinner plate. She did not understand why. She did not have family or caretakers nearby to …

A patient of mine was newly diagnosed with type 1 diabetes. He started on insulin and I taught him about glucose targets; insulin administration, including the signs and symptoms of hypoglycemia; and how to prevent, recognize, and treat hypoglycemia. I also taught him about the “honeymoon period,” which, I told …

The addition of a DPP-4 inhibitor decreased HbA1C while not requiring an increase in insulin, and subjects remained weight neutral without experiencing an increase in hypoglycemic events… Currently approved dipeptidyl peptidase-4 (DPP-4) inhibitors include alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin. DPP-4 inhibitors work by enhancing glucose dependent insulin secretion and …

Last week in the pharmacy we received an electronic refill authorization for regular and nph insulin.   The patient had been using the two insulins together for about two years and seemed to be in relatively good control. The refills had the sig code “uad”. Usually we would ask for …

Exenatide twice daily shows similar glycemic control with weight loss and less hypoglycemia as compared to mealtime insulin… Some patients with advanced type 2 diabetes still do not achieve glycemic control with insulin glargine and metformin. Mealtime insulin lispro is often added on to the regimen but it is associated …

A fall in insulin dose requirement in patients with preexisting diabetes can lead to increased risk of placental dysfunction… Women with preexisting diabetes typically experience an increased need for insulin during the later stages of pregnancy due to an increase in insulin resistance during this time. A drop in insulin …