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GLP-1 Agonist Therapy Center

GLP-1 Diabetes Drug Treatment: GLP-1 (glucagon-like peptide 1 receptor agonists) are incretin mimetics which have several benefits for diabetes management. They suppress post-prandial glucagon release, delay stomach emptying, and increase insulin sensitivity. Significantly lower rates of hypoglycemia accompany GLP-1 therapy. This class also has the side effect of modest weight reduction and reduction of systolic blood pressure. GLP-1 receptor agonists are counter-indicated for patients with a history of pancreatitis.

Patient’s Plan to “Stop All of My Medicine” Not a Good Idea…

The patient, a woman, 52 years of age, has type 2 diabetes and is on metformin, a GLP-1 agonist, and a long-acting insulin. Over the past few months, I’ve received calls and emails from her every now and then to let me know her glucose levels were rising, but whenever …

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GLP-1 Not As Effective after Roux-en-Y Gastric Bypass

Researchers compared glucose and hormonal responses to a liquid meal test in 20 obese participants with T2 who underwent RYGB or nonsurgical intensive lifestyle modification… Rapid glycemic improvements following Roux-en-Y gastric bypass (RYGB) are frequently attributed to the enhanced GLP-1 response, but causality remains unclear. To determine the role of …

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Effects of GIP and GLP-1 on Glucagon Response in Type 1 Diabetes

Glucose-dependent insulinotropic polypeptide and glucagon- like peptide-1 have glucose-dependent effects on glucagon secretion but differ in their effects on type 1 and type 2 diabetes patients… From various studies we know that glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have glucose-dependent effects on glucagon secretion. GIP causes increased glucagon …

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Type 2 Diabetes Control with GLP-1 Agonist and Basal Insulin Combination

Glucose regulation and weight management are very important factors when treating type 2 diabetes patients… Prior studies have shown that glucagon-like peptide receptor agonist are beneficial not only for better glucose control but also helpful in weight reduction in patients with type 2 diabetes. Other studies and recommendations on type …

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