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DPP-4 Therapy Center

Practical Diabetes Care, 3rd Ed., Excerpt #1: Diabetes in the Emergency Department


David Levy, MD, FRCP INTRODUCTION Every day many patients with established or newly diagnosed diabetes pass through emergency departments. Few require admission, but all need careful evaluation and management: emergencies in diabetes can develop rapidly, and they carry a risk of mortality. Deciding who needs admission requires clinical skill and experience. …

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DPP-4 Inhibitors in Combination with Insulin Therapy for Type 2 Diabetes Patients

The addition of a DPP-4 inhibitor decreased HbA1C while not requiring an increase in insulin, and subjects remained weight neutral without experiencing an increase in hypoglycemic events… Currently approved dipeptidyl peptidase-4 (DPP-4) inhibitors include alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin. DPP-4 inhibitors work by enhancing glucose dependent insulin secretion and …

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Metformin Is Best Initial Oral Drug for Lowering Glucose Levels in Diabetes Patients

Metformin, sulfonylureas, thiazolidinedione, and DPP-4 inhibitors were compared to evaluate the effects on the time to subsequent treatment… There are many classes of oral drugs used for diabetes therapy, but there is a lack of evidence as to which drug is best for use as initial therapy. Most patients diagnosed …

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