Oxyntomodulin: Partner to GLP-1?
Oxyntomodulin is a gut peptide released in response to a meal. It is synthesized within specialized enteroendocrine cells called L cells. Oxyntomodulin is released from the intestinal L cells 5-10 minutes after ingestion of food in amounts...
GLP-1 Special Series Editor's Note #7
There's been some interesting research on a compound that appears to be a partner peptide for GLP-1. Oxyntomodulin is released in response to a meal and seems to have a significant effect on glucose levels. Our current PharmD candidate, ...
An Eye-Opening Interview with Steven Edelman, MD, PART 2
This week, we present the second half of our publisher Steve Freed's interview with Dr. Steven Edelman...
GLP-1 Knowledge Survey Part V
Over the past few weeks we have been looking at your colleagues' responses to questions about GLP-1, including mechanisms, interactions, dosing and effectiveness. Over the next two weeks we will examine some of your opinions on starting doses...
Practical Strategies for Choosing among Incretin-Based Agents in Type 2 Diabetes, Part 2
PART 2: Mark, a 55-year-old white man, was diagnosed with type 2 diabetes 3 years ago. At the time of diagnosis his glycosylated hemoglobin (A1c) level was 7.5%, his body mass index (BMI) was 30 kg/m2, and his...
GLP-1 Knowledge Survey Part IV
When making a choice amongst GLP-1 Agonists, the number of injections per day and when peak concentrations are reached are both important in selecting therapy. There was almost unanimous consensus that Exenatide is administered twice daily...
GLP-1 Knowledge Survey Part III
This week we examine more of your responses regarding GLP-1 therapy....
GLP-1 Knowledge Survey Part I
Thanks to the great number of you who participated. As we put together the original survey our first thoughts were to find out what you wanted to know about GLP-1 analogs and what your impressions of the class of drugs...