Issue 456

Test Your Knowledge Issue 456

A 58-year-old woman has a body mass index of 27 at her annual examination. Her fasting blood glucose level is currently 116 mg/dL (6.44 mmol/L).

Dealing with Exercise-Induced Hypoglycemia

Too often our patients who are very active start to decrease their participation in sports and other physical endeavors. Frequently, this is because they are experiencing hypoglycemia and have no idea how to prevent this from happening. Sheri...

High Insulin Levels Increase Breast Cancer Risk

Postmenopausal women with hyperinsulinemia were at least two times more likely to develop breast cancer compared with women with the lowest insulin levels. Interventions that target insulin and its signaling pathways may decrease breast cancer risk...

Diabetes And Heart Disease: Risk Intertwined

The most common long-term complications of diabetes are problems with the heart and blood vessels, according to Mayo Clinic. No one dies from diabetes, most die from heart attacks and strokes.

Study Links Smoking While Pregnant to Increases in Offspring Diabetes and Obesity

Prenatal nicotine exposure through smoking or nicotine patches alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life.

Isis Initiates Clinical Trial Of First In Class Diabetes Drug SGLT2

Isis Pharmaceuticals, Inc. announced it has initiated a Phase 1 study of ISIS-SGLT2Rx, an antisense drug that inhibits the production of sodium dependent glucose co-transporter type 2 (SGLT2). This first in class diabetes drug, causes you to ...

Key To Treating Diabetes Is Making Muscles Burn Fat Better

Scientists have produced results that could silence the current debate about exactly how fat molecules clog up muscle cells, making them less responsive to insulin. The finding is an important milestone in understanding the mechanisms of obesity...

New Possible Anti-Inflammatory Drug for Poorly Controlled Type 2 Diabetes

Researchers in 20 medical centers across the country are enrolling adults with type 2 diabetes who have poorly controlled blood glucose to participate in a clinical study, Targeting Inflammation with Salsalate in Type 2 Diabetes (TINSAL-T2D).

Eggs Linked To Increased Diabetes Risk

People who sit down to a daily breakfast of eggs may have an increased risk of developing type 2 diabetes, new research suggests.

Optimal Exercise For Seniors’ Health Is Combo Of Resistance and Aerobics

In study, aerobics, resistance training lowered risk of insulin resistance and improved motor function.

Midlife Diabetes Increases Dementia Risk

Diabetes increases the risk for dementia, including vascular dementia and Alzheimer's disease (AD), by 125%, especially if onset is in midlife, a population-based study suggests.

New Diagnoses Provide Window of Opportunity for Health Behavior Changes

Older adults appear more likely to quit smoking or lose weight following a recent diagnosis of heart disease, diabetes or another serious condition, according to a new report.

Ongoing Statin Therapy Associated With Lower Risk of Death

Patients with high cholesterol levels who continually take statins appear to have a lower risk of death over four to five years, regardless of whether they already have diagnosed heart disease, according to a report

Inflammation Plays a Major Role in Diabetes

A key protein in the immune system pathway that effects the pancreas discovered.

Clinical Benefits Found From Treating Mild Gestational Diabetes

Treatment of mild gestational diabetes yields clinical benefit, a randomized trial showed. Although a composite endpoint of neonatal morbidity did not differ between the treatment group and the controls, rates of Caesarean delivery (P=0.021) and...

Hypertension Drug Dramatically Reduces Proteinuria in Kidney Disease Patients

Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a new study.

All Gifts to Doctors Totaling More Than $100/Year Must Be Disclosed

Drug and medical device manufacturers would need to publicly disclose all doctor payments and gifts exceeding $100 per year under U.S. legislation unveiled last week.