Issue 344

Test Your Knowledge Issue 344

There are now agents (either currently approved or investigational) that not only reduce blood glucose but also:

HbA1c Early in Diabetic Pregnancy Predicts Outcomes

In women with diabetes, increasing hemoglobin A1c (HbA1c) levels in early pregnancy are associated with increasing risk of adverse pregnancy outcomes, according to a new report.

Byetta Approved for Use with TZD’s in Type 2 Diabetes

Amylin and Eli Lilly announced last Friday that the FDA has approved BYETTA(R) (exenatide) injection as an add-on therapy to improve blood sugar control in people with type 2 diabetes who have not achieved adequate control on a thiazolidinedione (TZD).

Spine Shrinks Early in Diabetic Nerve Condition

The size of the spinal cord is significantly diminished long before symptoms of nerve damage appear in adults with diabetes, British doctors report.

New Gene May Contribute to Development of Type 2 Diabetes

Scientists from the new interdisciplinary LIMES (Life & Medical Sciences) Centre at the University of Bonn have identified a new gene which could play an important role in the development of diabetes.

Drug Treatment Slows Macular Vision Loss in Diabetics

A drug commonly used to slow the loss of central vision has shown promise in stemming a common precursor of blindness in diabetics, which involves the same central light-sensitive area of retina, scientists report.

Diabetes Control Maintained with Physical Activity

New study suggests that just twice a week resistance training is helpful for maintaining control of blood sugar levels in adults with type 2 diabetes.

Weight Loss Nasal Spray Begins Clinical Trials

PYY nasal spray trial demonstrates it produces satiety and a 30% reduction in calorie intake.

Diabetes Not Linked to Alzheimer's in Seniors

For older people with diabetes, the condition does not increase the likelihood that they'll develop Alzheimer's disease, according to a report in the medical journal Neurology.

Obesity Has a Microbial Component With Therapeutic Implications

Increasing 'lean microbiota can help in reducing obesity.

Ezetimibe/Simvastatin Lowers LDL-C More Than Atorvastatin in Diabetics

Patients treated with ezetimibe/simvastatin, 10/20 mg/d achieved significantly greater mean reductions in LDL-C levels (-53.6%) than those treated with atorvastatin, 10 mg/d (-38.3%; or 20 mg/d (-44.6%).

Understanding How ACE Inhibition Reduces Risk of Kidney Failure in Type 2’s

TGF-beta gene expression is a potential mechanism of the renoprotective effect of renin-angiotensin blockade.

Soy Yogurt Help to Control Diabetes

U.S. researchers reported that soy yogurt, especially with fruit in it, may help control both type 2 diabetes and high blood pressure.

Celiac Disease Triples Risk of Diabetes

Children with celiac disease have a higher likelihood of a subsequent diagnosis of type 1 (insulin-dependent) diabetes -- approximately 3-fold higher -- than the general population.

Treatment With Certain Anti-Hypertensive’s Can Reduce Alzheimer's Disease

A new cardiovascular drug screening has identified existing anti-hypertensive agents capable of preventing cognitive decline and amyloid neuropathology associated with Alzheimer's disease.

UN Passes Resolution Recognizing the Global Threat of the Diabetes Epidemic

UN Resolution Caps Momentous Year for Diabetes World