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Diabetes a Risk Factor for Peptic Ulcer Bleeding

Type 2 diabetes patients are at a higher risk for peptic ulcer bleeding…. 

An observational retrospective cohort study was performed using the National Health Insurance Research Database of Taiwan records for 5,699 type 2 diabetic patients matched in a 1:2 ratio to assess whether or not type 2 diabetic patients are at higher risk for developing peptic ulcer bleeding and to identify possible risk factors.

Findings from this study showed that type 2 diabetics had a significantly higher rate of peptic ulcer bleeding than did controls during a 7 year follow-up period. Diabetes was shown to be independently associated with increased risk of peptic ulcer bleeding demonstrated by a hazard ratio of 1.44.

Risk factors for peptic ulcer bleeding in diabetic patients included age, chronic renal disease, history of peptic ulcer disease, and use of non-steroidal anti-inflammatory drugs.

Peng YL, Leu HB, Luo JC, Huang CC, Hou Mc, Lee FY Diabetes is an independent risk factor for peptic ulcer bleeding : a nationwide population-based cohort study. J Gastroenterol Hepatol. 2013 Mar 11. doi: 10.1111/jgh.12190