Type 2 Diabetes

Use of blue LED light activates sulfonylureas… The use of sulfonylureas has long been an option for controlling type 2 diabetes. Their use is often associated with hypoglycemia and weight gain. A new technology seeks to minimize these side effects. Researchers are looking at a prototype sulfonylurea, JB253, which stimulates …

Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …

In an analysis using genetic data from over 25 different studies involving diabetes patients, researchers can find no causal association between higher vitamin D levels and lower diabetes risk… Low circulating concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, have been associated with an increased risk of …

  Socioeconomic status plays a role in how strong the association is…. Previous studies have shown an association between working longer hours and risk factors that can contribute to type 2 diabetes incidence. These risk factors included physical inactivity, unhealthy lifestyle, poor nutritional choices, and cardiovascular disease. Other studies have …

  SGLT-2 inhibitor use in the management of glucose in type 2 diabetes could reduce blood pressure in patients with hypertension…. In a new study, researchers found that empagliflozin lowered blood pressure in patients with type 2 diabetes and hypertension. Hypertension affects about two-thirds of patients with diabetes. See more …

Typically when we diagnose a type 2 patient we start on the normal pathway of metformin and “diet and exercise” modifications. For many of our patients this regimen makes a significant improvement in their glucose levels and A1c values…. But for those patients who don’t improve, we are then forced …

Phase 3 trial demonstrates the safety and efficacy of albiglutide in type 2 diabetes patients with renal impairment…. Renal impairment is a common comorbid condition in type 2 diabetes patients with reported incidence rates as high as 35%. Those with renal insufficiency often find their diabetes treatment options limited. Possible …

Type 2 diabetes patients on a low-carb diet had improvements in physical function, pain reduction, and overall health after 12 months…. 

FREEDOM-1 and FREEDOM-1 High Baseline (HBL) study showed positive results when the continuous subcutaneous infusion of exenatide is added to standard oral diabetes medications….  ITCA 650 is a continuous subcutaneous infusion of exenatide through a pump for the treatment of type 2 diabetes. FREEDOM-1 is a double blinded, randomized, placebo-controlled, multicenter, phase …

Gout appears to increase the risk of type 2 diabetes, especially in women….  Researchers followed more than 35,000 gout sufferers in the United Kingdom and found that women with gout were 71 percent more likely to develop diabetes compared with people without gout. For men, the increased risk was 22 …