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Type 2 Diabetes

Type 2 Diabetes Research and News: Type 2 diabetes is a metabolic disorder. Though most commonly diagnosed in the elderly, younger adults and even children are increasingly subject to the disease. 9.4% of the US population has Type 2 diabetes or about 30 million Americans. Approximately 95% of all adults diagnosed with diabetes have Type 2. New tools, techniques and treatments can help you improve outcomes for your Type 2 diabetes patients.

Blocking a Genetic Variant Associated with Type 2 Diabetes May Improve Insulin Secretion

Yohimbine, a α2A-adrenergic receptor agonist, showed a 29% increase in insulin secretion in patients with type 2 diabetes related to the genetic variation… The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type …

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Vitamin D and Type 2 Diabetes Risk

In an analysis using genetic data from over 25 different studies involving diabetes patients, researchers can find no causal association between higher vitamin D levels and lower diabetes risk… Low circulating concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, have been associated with an increased risk of …

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GLP-1 Receptor Agonist a Treatment Option in Type 2 Patients with Renal Insufficiency

Phase 3 trial demonstrates the safety and efficacy of albiglutide in type 2 diabetes patients with renal impairment…. Renal impairment is a common comorbid condition in type 2 diabetes patients with reported incidence rates as high as 35%. Those with renal insufficiency often find their diabetes treatment options limited. Possible …

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Two Positive Phase 3 Trials for ITCA 650, a GLP-1 Agonist, in Type 2 Diabetes

FREEDOM-1 and FREEDOM-1 High Baseline (HBL) study showed positive results when the continuous subcutaneous infusion of exenatide is added to standard oral diabetes medications….  ITCA 650 is a continuous subcutaneous infusion of exenatide through a pump for the treatment of type 2 diabetes. FREEDOM-1 is a double blinded, randomized, placebo-controlled, multicenter, phase …

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Gout Linked to Increased Type 2 Diabetes Risk

Gout appears to increase the risk of type 2 diabetes, especially in women….  Researchers followed more than 35,000 gout sufferers in the United Kingdom and found that women with gout were 71 percent more likely to develop diabetes compared with people without gout. For men, the increased risk was 22 …

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