Type 1 Diabetes

By closely examining currently used diagnostic criteria, researchers evaluated whether it might be possible to diagnose type 1 earlier…. Today, diagnostic criteria for type 1 diabetes includes a glucose value ≥ 126 mg/dL and 2-h glucose values ≥ 200 mg/dL. These glucose values were selected because they correspond with observed …

It may be possible to predict the development of type 1 diabetes in young children by measuring the presence of autoantibodies in the blood… This comes from new data from The Environmental Determinants of Diabetes in the Young (TEDDY) study. Lead researcher Åke Lernmark, MD, PhD, of Lund University, said …

David Levy, MD, FRCP Insulin Pump Treatment (CSII) First used at the end of the 1970s, insulin pump therapy is standard treatment for type 1 diabetes, although use varies between countries (e.g. about 1–2% in the UK, probably more now; about 25% in USA, up to 40% in Norway). Only rapid-acting …

A novel insulin that automatically adjusts blood sugar may mitigate some of the complications associated with insulin dosing for patients with type 1 diabetes… Self-administered insulin is the most important therapeutic to provide control over blood glucose levels for patients with type 1 diabetes. However, standard insulin therapy introduces a …

A recent study discovers that there may be an association between breastfeeding and lowering risk of type 1 diabetes… The objective of this study was to determine the association of breast feeding duration with the risk of type 1 diabetes in genetically predisposed newborns. In addition, this study looked at …

David Levy, MD, FRCP Introduction Insulin treatment in type 1 diabetes is substitution/replacement hormone treatment, but replacement is much more variable and difficult to achieve than in other hormone deficiencies (e.g. thyroid, adrenal, gonadal hormones) because of the minute-by-minute variation in insulin secretion by the intact pancreas, which cannot yet be …

Why is cancer risk higher among diabetes patients?… Evidence indicates an increased risk of certain cancers among people with type 2 diabetes. Evidence for rarer cancers and for type 1 diabetes is limited. Australian researchers recently explored the excess risk of site-specific cancer incidence and mortality among people with type …

Optimum HbA1c level yet to be determined… HbA1c is strongly related to the development of diabetes complications, but it is still controversial as to which HbA1c level to strive for in the treatment of type 1 diabetes. Swedish researchers evaluated HbA1c, followed from diagnosis, as a predictor of severe microvascular …

However, advancement in medications and better controlled regimens may be contributing to a decline in psychiatric disorders among this population… We know from previous studies and research that there is a increased risk and prevalence for depression in the diabetic population. Other trials have also linked diabetes with different subtypes …

Glucose-dependent insulinotropic polypeptide and glucagon- like peptide-1 have glucose-dependent effects on glucagon secretion but differ in their effects on type 1 and type 2 diabetes patients… From various studies we know that glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have glucose-dependent effects on glucagon secretion. GIP causes increased glucagon …