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Prediabetes

Prediabetes Research and Treatment Methods: Prediabetes is defined as having an HbA1c between 5.7 and 6.4% or a fasting glucose between 100 and 126 mg/dl. According to the NDEP, approximately 86 million people in the US have prediabetes. These people are subject to many of the same risks as diabetes patients. Prediabetes typically progresses to diabetes if the patient’s lifestyle remains the same. Beta cell destruction occurs, and the patient’s ability to maintain glucose homeostasis is further compromised. For this reason and others, many professionals believe that prediabetes is mislabeled and should be considered diabetes. New tools, techniques and guidance can help you improve outcomes for your prediabetes patients.

Two MicroRNAs Identify Prediabetes

Serum levels of 2 microRNAs, miR-192 and miR-193b, can be used to identify individuals with prediabetes, researchers report… The uncontrolled hyperglycemic excursions associated with prediabetes are stressful for the body, and miRNAs are thought to be critical regulators of stress. Dr. Marcelina Párrizas from Diabetes and Obesity Research Laboratory, Barcelona, …

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Diabetes Mellitus 101 for Cardiologists, Part 8

In this week’s Homerun Slides, Dr. Stanley Schwartz reviews pioglitazone as a therapy for both diabetes and cardiovascular issues. Topics include: Pioglitazone in Dysmetabolic Syndrome, Prediabetes, Type 2 Diabetes; Effect of Pioglitazone on Cardiac Mass and Function: and Glitazones (including rosiglitazone) and Cardiac Function…. To download these slides in PowerPoint (.ppt) format, …

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Hyperglycemia and Incidence of Subclinical Myocardial Damage

Hyperglycemia associated with myocardial damage appears to begin before the diagnosis of diabetes and requires a highly sensitive assay to detect it… Cardiovascular disease is the leading cause of death among individuals with diabetes. Hyperglycemia is believed to induce coronary microvascular dysfunction and result in myocardial injury. Previous studies have …

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