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Coffee Drinkers at Reduced Risk of Type 2 Diabetes

Jan 19, 2012

Scientists are offering a new solution to that long-standing mystery as to why heavy coffee drinkers have a lower risk of developing type 2 diabetes. Ling Zheng, Kun Huang and colleagues explain that previous studies show that coffee drinkers are at a lower risk for developing type 2 diabetes, which accounts for 90-95% of diabetes cases in the world. Those studies show that people who drink four or more cups of coffee daily have a 50% lower risk of type 2 diabetes. And every additional cup of coffee brings another decrease in risk of almost 7%. Scientists have implicated the misfolding of a substance called human islet amyloid polypeptide (hIAPP) in causing type 2 diabetes, and some are seeking ways to block that process. Zheng and Huang decided to see if coffee’s beneficial effects might be due to substances that block hIAPP. They identified two categories of compounds in coffee that significantly inhibited hIAPP and suggest that this effect explains why coffee drinkers show a lower risk for developing diabetes. “A beneficial effect may thus be expected for a regular coffee drinker,” the researchers conclude. ACS’ Journal of Agricultural & Food Chemistry, Jan. 2012