Carbohydrate Restriction May Reverse Prediabetes

Aug 18, 2020

Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Brianna Belton, PharmD. Candidate, Florida Agricultural & Mechanical University, College of Pharmacy and Pharmaceutical Sciences

Studies show that carbohydrate restriction for prediabetes can lead to normal glucose levels, reduce the progression to type 2 diabetes, and decrease the prevalence of metabolic syndrome.

In a single-arm, prospective, longitudinal study, the effects of carbohydrate restriction were analyzed two years after treatment. This study was done with a remotely delivered continuous care intervention (CCI) that emphasized carbohydrate restriction and weight loss to patients with prediabetes. Researchers assessed the incidence of regression from prediabetes to normoglycemia, progression from prediabetes to type 2 diabetes, and the prevalence of metabolic syndrome after two years of treatment. 116 patients who were class II or greater obesity with prediabetes were enrolled in this study. Prediabetes was defined as HbA1c < 6.5% with metformin use of HbA1c 5.7-6.4% without diabetes medication....

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