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Production Assistant, Diabetes In Control

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #54: Incretin Physiology in Health and Disease Part 4 of 6

Central nervous effects: A role for GLP-1 in the central nervous regulation of food intake has been inferred from the high density of GLP-1 receptors in the hypothalamus. Also, direct intracerebroventricular administration of GLP-1 has caused a significant reduction in food intake in rats, and these actions could be abolished by co-administration of the GLP-1 receptor antagonist exendin.

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GLP-1 Recommendations

How comfortable are you in recommending the combination of a GLP-1 receptor agonist along with glargine insulin? 1- Very comfortable 2- Slightly comfortable 3- Neutral 4- Slightly uncomfortable 5- Very uncomfortable at this time Follow the link to share your response and see what your colleagues think!

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Question #863

Test Your Knowledge

Please select the drug class that best fits the description. This injectable drug class leads to increased insulin secretion, decreased glucagon secretion and slowed gastric emptying. One of its advantages is that its use can lead to weight loss: 1. DPP-4 inhibitors 2. GLP-1 receptor agonists 3. Dopamine-2 Agonists 4. SGLT-2 Inhibitors Did you get it right? Follow the link to find out!

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