Monday , December 18 2017
Home / Production Assistant, Diabetes In Control (page 62)

Production Assistant, Diabetes In Control

Question 843

Test Your Knowledge

In the fasting state, hyperglycemia is directly related to: 1. Increased hepatic glucose production 2. Defective insulin stimulation of target tissue glucose disposal 3. Decreased adipocyte lipolysis 4. Loss of pancreatic α-cell functionality Did you get it right? Follow the link to find out!

Read More »

Cancer Prevention

Do you promote the use of metformin to help prevent cancer as well as to control blood sugars? Follow the link to share your opinion and see what your colleagues think!

Read More »

What’s Important to Your Patient?

Male, 26 years of age, type 2 diabetes, obesity, hyperlipidemia, hypertension. Strong family history of type 2 diabetes with complications. Has been a patient since diagnosed 2 years ago. Has met with dietitian. Hasn’t made dietary changes, increased activity, or taken meds prescribed to lower his glucose. A1C 9.2% and rising every 3 months. He would also miss many of his appointments. Stated, “Nothing is going to bother me. Maybe it did my family, but that was a different time and it’s not going to happen to me. I’m going to go on enjoying my life.”

Read More »

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #33: Beta-Cell biology of insulin secretion Part 3 of 5

Dynamics of insulin secretion: Biphasic insulin secretion -- insulin release from pancreatic beta cells in response to glucose is characterized by biphasic kinetics: an initial component (1st phase), which develops rapidly but lasts only a few minutes, followed by a sustained component (2nd phase). It has been thought that the biphasic response of insulin secretion reflects primarily the dynamics of spatially and functionally distinct insulin granules. The prevailing hypothesis is that the 1st phase of insulin secretion is attributable to fusion of predocked granules from a readily releasable pool (RRP) that accounts for less than 5% of total granules, while the 2nd phase involves recruitment of granules from a more distant reserve pool (RP) that accounts for the great majority of total granules.

Read More »