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Managing Editor, Diabetes in Control

Managing Editor, Diabetes in Control

Introduction: Anthony Cincotta

I am a neuroendocrinologist by training, having received my Bachelor’s degree in biochemistry and molecular biology from the University of California, Santa Barbara and Master’s and Doctorate degrees from Louisiana State University (LSU) in physiology under the mentorship of Dr. Albert H. Meier. It was at LSU that my interest in the biological clock system and its role in the regulation of metabolic physiology was sparked by the revolutionary discoveries and elucidations made by Dr. Meier’s lab concerning biological clock mechanisms regulating physiology. He and his group in the early 1960s were the very first to demonstrate the existence in any organism of circadian rhythms of physiological responses to neuroendocrine factors. At LSU, I began investigating the possibility that modern human pathology of the metabolic syndrome (and several other progressive pathologies) was not a result of any “genetic defect” but of an environmentally induced (e.g., diet, stress, sleep-wake architecture) alteration of circadian neuroendocrine information presented to the clock system that then responded to direct the body to the obese/insulin resistant state as a survival response to such information.

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Question #853

Test Your Knowledge

The development of type 2 diabetes is multifactorial. All of the following are thought to play a role in the development EXCEPT: 1. Genetics 2. Environmental factors 3. Elevated circulating free fatty acid levels 4. Pancreatic α-cell defects 5. Increased skeletal GLUT4 glucose transporters translocation capacity Did you get it right? Follow the link to find out!

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Missing the Point

Friend of Diabetes in Control and frequent guest author David Kliff, Diabetic Investor, shared his views on some of the news coming out of EASD. As always, his ideas are thought-provoking. We reached out to some of our Advisory Board members to get their responses to David’s piece, and they provided additional strong viewpoints for your consideration.

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Question #851

Test Your Knowledge

Issue849Graph Here's another test of your graph-interpreting skills! Follow the link to see this graph at full size and indicate the parameter that best describes Curve 3. 1. Insulin Secretion 2. Postprandial glucose 3. Fasting glucose 4. Insulin Resistance

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