Main Newsletter
Mastery Series
Therapy Series
 
Bookmark and Share | Print Article | Items for the Week Previous | All Articles This Week | Next
This article originally posted and appeared in  DietType 2 DiabetesPreventionIssue 647

Vitamin K1 Reduces Risk of Type 2 by 50 Percent

Adding foods or supplements rich in vitamin K1 (phylloquinone) may help protect against type 2 diabetes....
Advertisement

The study found that high intake of the vitamin can slash the risk developing type 2 diabetes in half.

The scientists report that for every 100 micrograms per day increase in the intake of vitamin K1, the risk of developing diabetes decreased by 17%.

For the analysis, N. Ibarrola-Jurado, of Universitat Rovira i Virgili in Reus, Spain, and colleagues studied data from over 1900 elderly men and women in the Prevention with the Mediterranean Diet Trial at high cardiovascular disease risk, and a further 1069 people who were free of diabetes at baseline.

Participants who increased their dietary intake of vitamin K1 during the 5-year follow-up were found to be 51 per cent less likely to develop type 2 diabetes than those who lowered or did not change their intake.

Cross-sectional associations were tested in 1925 men and women in the Prevention with the Mediterranean Diet trial. A longitudinal analysis was conducted on 1069 individuals free of diabetes at baseline (median follow-up: 5.5 y). Biochemical and anthropometric variables were obtained yearly. Dietary intake was collected during each annual visit by using a food-frequency questionnaire, and phylloquinone intake was estimated by using the USDA database. The occurrence of type 2 diabetes during follow-up was assessed by using American Diabetes Association criteria.

Dietary phylloquinone at baseline was significantly lower in subjects who developed type 2 diabetes during the study. After adjustment for potential confounders, risk of incident diabetes was 17% lower for each additional intake of 100 μg phylloquinone/d. Moreover, subjects who increased their dietary intake of vitamin K during the follow-up had a 51% reduced risk of incident diabetes compared with subjects who decreased or did not change the amount of phylloquinone intake.

The researchers concluded that "dietary phylloquinone intake is associated with reduced risk of type 2 diabetes."

Vitamin K1 is one type of the naturally occurring Vitamin K, which is found high in green vegetables including raw spinach, raw leaf lettuce, raw kale, raw Swiss chard, raw watercress, raw parsley and cooked broccoli.

First published October 3, 2012, doi: 10.3945/‚Äčajcn.111.033498 Am J Clin Nutr November 2012 ajcn.033498 

Advertisement


 

Bookmark and Share | Print | Category | Home

This article originally posted 12 October, 2012 and appeared in  DietType 2 DiabetesPreventionIssue 647

Past five issues: Diabetes Clinical Mastery Series Issue 208 | Issue 748 | GLP-1 Special Editions September 2014 | Diabetes Clinical Mastery Series Issue 207 | Issue 747 |

2014 Most Popular Articles:

Abbott Announces Approval of Its New Unique Continuous Glucose Monitor
Posted September 05, 2014
Low Carb Beats Low Fat
Posted September 05, 2014
FDA Approves Bupropion/Naltrexone (Contrave) for Obesity by Orexigen Therapeutics
Posted September 12, 2014
Lilly's Basal Insulin Peglispro Demonstrated HbA1c Superiority against Lantus
Posted September 05, 2014
FDA Approves Once-Weekly GLP-1 Diabetes Treatment Regimen for T2DM
Posted September 25, 2014
An Exclusive Interview with Al Mann, Founder and CEO, Mannkind Corp.
Posted September 15, 2014
Sleeve Gastrectomy Now a Common Choice for Bariatric Surgery
Posted September 12, 2014
Type 2 Diabetes Diagnosis Needs to Be Changed: Prediabetes=Diabetes
Posted September 12, 2014
High-salt Diet and High HBA1c May Increase Cardiovascular Disease
Posted September 19, 2014
Predicting Which Diabetics Will Develop Major Complications
Posted September 05, 2014


Browse by Feature Writer & Article Category.
A. Lee Dellon, MD | Aaron I. Vinik, MD, PhD, FCP, MACP | Beverly Price | Charles W Martin, DD | Derek Lowe, PhD | Dr. Brian Jakes, Jr. | Dr. Fred Pescatore | Dr. Tom Burke, Ph.D | Eric S. Freedland | Evan D. Rosen | Ginger Kanzer-Lewis | Greg Milliger | Kristina Sandstedt | Laura Plunkett | Leonard Lipson, M.A. | Louis H. Philipson | Maria Emanuel Ryan, DDS, PhD | Marilyn Porter, RD, CDE | Melissa Diane Smith | Michael R. Cohen, RPh, MS, ScD, FASHP | Paul Chous, M.A., OD | Philip A. Wood PhD | R. Keith Campbell, Professor, B.Pharm, MBA, CDE | Richard K. Bernstein, MD | Sheri R. Colberg PhD | Sherri Shafer | Stanley Schwartz, MD, FACP, FACE | Steve Pohlit | Steven V. Edelman, M.D. | Timothy S. Hollingshead |

Cast Your Vote
Now that once-weekly dulaglutide has been approved, will you be prescribing it?
CME/CE of the Week
Hugh G. Calkins, MD, and Joseph Edward Marine, MD

Category: Cardiology
Credits:
 1



Search Articles On Diabetes In Control