Main Newsletter
Mastery Series
Therapy Series
 
Bookmark and Share | Print Article | Items for the Week Previous | All Articles This Week | Next
This article originally posted and appeared in  DietType 2 DiabetesPreventionIssue 647

Vitamin K1 Reduces Risk of Type 2 by 50 Percent

Adding foods or supplements rich in vitamin K1 (phylloquinone) may help protect against type 2 diabetes....
Advertisement

The study found that high intake of the vitamin can slash the risk developing type 2 diabetes in half.

The scientists report that for every 100 micrograms per day increase in the intake of vitamin K1, the risk of developing diabetes decreased by 17%.

For the analysis, N. Ibarrola-Jurado, of Universitat Rovira i Virgili in Reus, Spain, and colleagues studied data from over 1900 elderly men and women in the Prevention with the Mediterranean Diet Trial at high cardiovascular disease risk, and a further 1069 people who were free of diabetes at baseline.

Participants who increased their dietary intake of vitamin K1 during the 5-year follow-up were found to be 51 per cent less likely to develop type 2 diabetes than those who lowered or did not change their intake.

Cross-sectional associations were tested in 1925 men and women in the Prevention with the Mediterranean Diet trial. A longitudinal analysis was conducted on 1069 individuals free of diabetes at baseline (median follow-up: 5.5 y). Biochemical and anthropometric variables were obtained yearly. Dietary intake was collected during each annual visit by using a food-frequency questionnaire, and phylloquinone intake was estimated by using the USDA database. The occurrence of type 2 diabetes during follow-up was assessed by using American Diabetes Association criteria.

Dietary phylloquinone at baseline was significantly lower in subjects who developed type 2 diabetes during the study. After adjustment for potential confounders, risk of incident diabetes was 17% lower for each additional intake of 100 μg phylloquinone/d. Moreover, subjects who increased their dietary intake of vitamin K during the follow-up had a 51% reduced risk of incident diabetes compared with subjects who decreased or did not change the amount of phylloquinone intake.

The researchers concluded that "dietary phylloquinone intake is associated with reduced risk of type 2 diabetes."

Vitamin K1 is one type of the naturally occurring Vitamin K, which is found high in green vegetables including raw spinach, raw leaf lettuce, raw kale, raw Swiss chard, raw watercress, raw parsley and cooked broccoli.

First published October 3, 2012, doi: 10.3945/‚Äčajcn.111.033498 Am J Clin Nutr November 2012 ajcn.033498 

Advertisement


 

Bookmark and Share | Print | Category | Home

This article originally posted 12 October, 2012 and appeared in  DietType 2 DiabetesPreventionIssue 647

Past five issues: Issue 760 | Diabetes Clinical Mastery Series Issue 219 | SGLT-2 Inhibitors Special Edition December 2014 | Issue 759 | Diabetes Clinical Mastery Series Issue 218 |

2014 Most Popular Articles:

New Guidelines for Doctors to Treat Diabetes
Posted December 12, 2014
Handbook of Diabetes, 4th Ed., Excerpt #20: Foot Problems in Diabetes
Posted November 29, 2014
Why Are Up to 20% Type 2's Nonresponsive to Exercise?
Posted December 05, 2014
Is Type 2 Diabetes an Inflammatory Disease?
Posted November 21, 2014
Carbs Associated with Higher Diabetes and Heart Disease Risk Factor
Posted December 05, 2014
Handbook of Diabetes, 4th Ed., Excerpt #19: Macrovascular Disease in Diabetes
Posted November 23, 2014
Any Pain Medication Said Effective When Treating Diabetic Nerve Pain
Posted November 21, 2014
Knowledge of Onset, Peak, and Duration of Action of Meds Prevents a Trip to the ER
Posted November 24, 2014
Link between Free Fatty Acids and Acute MI, Type 2 Diabetes
Posted November 21, 2014
New Approach Targets Type 2's Poorly Controlled With Metformin
Posted November 14, 2014


Browse by Feature Writer & Article Category.
A. Lee Dellon, MD | Aaron I. Vinik, MD, PhD, FCP, MACP | Beverly Price | Charles W Martin, DD | Derek Lowe, PhD | Dr. Brian Jakes, Jr. | Dr. Fred Pescatore | Dr. Tom Burke, Ph.D | Eric S. Freedland | Evan D. Rosen | Ginger Kanzer-Lewis | Greg Milliger | Kristina Sandstedt | Laura Plunkett | Leonard Lipson, M.A. | Louis H. Philipson | Maria Emanuel Ryan, DDS, PhD | Marilyn Porter, RD, CDE | Melissa Diane Smith | Michael R. Cohen, RPh, MS, ScD, FASHP | Paul Chous, M.A., OD | Philip A. Wood PhD | R. Keith Campbell, Professor, B.Pharm, MBA, CDE | Richard K. Bernstein, MD | Sheri R. Colberg PhD | Sherri Shafer | Stanley Schwartz, MD, FACP, FACE | Steve Pohlit | Steven V. Edelman, M.D. | Timothy S. Hollingshead |

Cast Your Vote
For your prediabetes patients who can't lower their blood glucose with lifestyle changes, do you prescribe GLP-1s or SGLT-2s?
CME/CE of the Week
Hugh G. Calkins, MD, and Joseph Edward Marine, MD

Category: Cardiology
Credits:
 1



Search Articles On Diabetes In Control