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This article originally posted 24 March, 2012 and appeared in  Issue 403

Test Your Knowledge Answer #403

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The correct answer is (E)

The patient had one randomly measured blood glucose value greater than 200 mg/dL (11.1 mmol/L), which indicates a need for further testing to establish the diagnosis of diabetes. A fasting blood glucose measurement is the preferred test to establish the diagnosis because of its ease of administration. A blood glucose level greater than 126 mg/dL (6.99 mmol/L) after 8 to 10 hours of fasting establishes the diagnosis of diabetes; the test should be repeated on another day to confirm the diagnosis. If a fasting blood glucose measurement indicates glucose intolerance in a high-risk patient such as this one (i.e., Hispanic, family history of diabetes, history of large babies, obesity), an oral blood glucose tolerance test should be performed. A 2-hour post-load value of 200 mg/dL (11.1 mmol/L) or greater on this test is considered positive for the diagnosis of diabetes. If the patient has glucose intolerance evident in blood glucose levels between the normal and diabetes ranges, education and counseling for lifestyle modifications should be offered because these strategies can delay or prevent progression to diabetes.
 
Key Point:
  • Measurement of fasting blood glucose is the test of choice in screening for diabetes. Glucose tolerance tests should be used in situations when diagnosis is suspected but fasting glucose is normal.
Fingerstick blood glucose measurement, although useful to monitor blood glucose levels, is unreliable for the purpose of diagnosis. Similarly, obtaining another random blood glucose measurement will not help establish the diagnosis. Neither a fingerstick test nor a hemoglobin A1C value is reliable to screen for or diagnose diabetes, and repeating these tests is not indicated. 
 
Bibliography
  1. American Diabetes Association. Standards of medical care in diabetes—2006. Diabetes Care. 2006;29 Suppl 1:S4-42. [PMID: 16373931] [PubMed]
Copyright © 2007 Diabetes In Control, Inc.  

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This article originally posted 24 March, 2012 and appeared in  Issue 403

Past five issues: Diabetes Clinical Mastery Series Issue 137 | Issue 677 | Diabetes Clinical Mastery Series Issue 136 | Issue 676 | Diabetes Clinical Mastery Series Issue 135 |

 
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