This article originally posted 12 July, 2005 and appeared in Issue 268
Bowel Cancer Risk Higher for Men with Diabetes
Having diabetes apparently raises men's risk of developing colorectal cancer.
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Lead investigator Susanna C. Larsson stated that, "Our findings suggest that
colorectal cancer may be added to the list of diabetes complications."
Ms. Larsson of the Karolinska Institute, Stockholm, and her colleagues note in
the journal Diabetes Care that some, but not all, epidemiological studies have
detected an increased risk of colorectal cancer in people with diabetes.
To investigate further, the researchers followed 45,550 men who were enrolled
in a population-based study in 1997 when they were 45 to 79 years of age.
During an average follow-up of 6 years, there were 411 cases of colorectal cancers.
After factoring in age and other variables, the researchers found that diabetes
was associated with a 49 percent higher likelihood of developing both colon and
rectal cancer.
These findings, the team concludes, "support the hypothesis" that high
insulin levels or factors related to insulin resistance may play a role in triggering
colon cancer.
Diabetes Care, July 2005.
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