Monday , November 20 2017
Home / Resources / Test Your Knowledge / Antihyperglycemic Medications for Patients with Type 2 Diabetes

Antihyperglycemic Medications for Patients with Type 2 Diabetes

The American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) list a hierarchy of usage for antihyperglycemic medications after metformin. Which one of the following lists shows the correct hierarchy, beginning with the most preferred?

Correct

Correct Answer: A

Explanation: The AACE and ACE guidelines recommend individualizing treatment after metformin, but they do offer the following hierarchy: GLP-1 RAs, SGLT-2 inhibitors, DPP-4 inhibitors, TZDs, and basal insulins. GLP-1 RAs are at the top of the hierarchy because of their weight loss properties and low risk for hypoglycemia.  Inzucchi SE, et al. Diabetes Care. 2015;38(1):140-149.

Garber AJ, et al. Endocr Pract. 2016;22(1):84-113. After Metformin: Choosing the Next Hypoglycemic Medication

Incorrect