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Aaron Vinik Part 6, Early Signs of Heart Disease




In part 6 of this Exclusive Interview, Dr. Aaron Vinik talks with Diabetes in Control Publisher Steve Freed during the AACE 2017 convention in Austin, Texas about the ability to predict cardiovascular disease.

Aaron Vinik, MD, PhD, FCP, MACP is the Director of Research and Professor of Medicine, Pathology and Neurobiology at Eastern Virginia Medical School in Norfolk, Virginia. His research and recent discovery of a gene, INGAP, could prove to be a cure for diabetes.

Transcript of this video segment:

Steve Freed: We have a number of biomarkers for cardiovascular disease and a number of blood tests. Are we truly able to predict cardiovascular disease and if so, obviously some of these new drugs might be a benefit thing even before they show the first signs of cardiovascular event.

Dr. Vinik: So, if you were to just use the traditional risk factors, say for cardiovascular disease — the dyslipidemia, the elevated LDL, the elevated triglycerides, the lower HDL,  the smoking, the hypertension, the increased abdominal girth, the insulin resistance — you put all those as traditional risk factors you can estimate about 24% of the risk, 76 percent of the time, you fail to estimate the risk. So we need a biomarker or markers that would do a better job on the remaining people. So, without giving away what I’m going to say tomorrow, I’m just telling you that with the very simple measures of heart rate, QTc interval, heart rate variability, autonomic function, you can get the prediction factor up 443%. Then, we have a much better risk calculator.

To view other segments in this video series:

Part 1: INGAP Research

Part 2: Heart Failure and Diabetes

Part 3: Reversing Heart Disease

Part 4: Cycloset

Part 5: Wonder Drug: SGLT-2 Inhibitor and GLP-1 Agonist