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A Link Between ESRD and Low BMI

Jun 13, 2020
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Chardae Whitner, 2020 PharmD. Candidate, Lake Erie College of Osteopathic Medicine

Study of BMI and ESRD suggests obesity may provide a health benefit when it comes to end-stage renal disease. 

Type 2 diabetes and obesity are a significant health problem worldwide.  It is known that type 2 diabetes (T2D) is one of the leading causes of renal failure, including chronic kidney disease and end-stage renal disease (ESRD).  However, some data shows that there is an inverse association between obesity and chronic kidney disease or ESRD.  There are limited studies that compare the effect of obesity on the risk of ESRD in patients with and without T2D.  Therefore, Yang-Hyun Kim et al. sought to evaluate the association between BMI and the risk of ESRD according to the glycemic status of the participants.  The researchers also examined the association between BMI and the risk of ESRD according to the presence of T2D in sustained BMI groups, because high variability of BMI was associated with the development of ESRD in the general population....


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