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From the Editor

March, 2017

  • 25 March

    March 25, 2017

    dave

    Most of the time when we speak about patients who are not diagnosed with diabetes and who develop complications, we are usually referring to vision changes or things like neuropathy. However, it now appears that there are a good number of these undiagnosed who die from ketoacidosis. This week, our ...

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March, 2017

Test Your Knowledge

Question #878

The diabetes drug empagliflozin reduces all of the following CV risk factors except:

Correct

Answer: c. Low-density lipoprotein cholesterol

Explanation:  Empagliflozin is the only diabetes medication that is approved by the US Food and Drug Administration for both glycemic control and cardiovascular death risk reduction in adult patients with type 2 diabetes and cardiovascular disease. However, dose-related increases in low-density lipoprotein cholesterol have been observed in patients taking the drug. In clinical trials, low-density lipoprotein cholesterol increased by 2.3%, 4.6%, and 6.5% in patients treated with placebo, empagliflozin 10 mg, and empagliflozin 25 mg, respectively.

JARDIANCE® (empagliflozin) Prescribing Information. http://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Jardiance/jardiance.pdf. Accessed February 6, 2017.

Briand F, et al. Diabetes. 2016;65(7):2032-2038.   Briand F, et al. Diabetes. 2016;65(7):2032-2038.

Monthly Essentials: Empagliflozin and CV Death in Type 2 Diabetes

Incorrect

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March, 2017