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Daily Archives: Mar 5, 2019

March 5, 2019

Last week, we had some information on the Da Qing Diabetes study, and I mentioned the problem with availability of the most popular ARB’s. Many of you asked for more information and we are completing a special report on what is going on and some possible solutions. Look to our …

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Consider More Accountability as a Treatment for Some Patients

Male, 57 years of age, type 2 diabetes. He started with us 6 months ago. When he started seeing us, he was taking  glipizide 10mg twice a day and metformin 1,000 twice daily for his glucose. His A1C was 7.5%, his BMI was 24. We stopped his glipizide and started him on a SGLT-2 and a weekly GLP-1. He met with the dietitian and made some big dietary changes, at least at the start. He also started wearing a CGM and was in our remote monitoring program. He sent me his CGM readings weekly for 4 months. He was doing so well, we decided he need not send me his weekly numbers but rather we’d review during his visits.

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Tim Dunn 2018 Complete Interview

Tim Dunn, Ph.D., is the director of Clinical and Computational Research and an Abbott Volwiler Research Fellow.  He also serves as Chair of the Scientific Research Review Committee for investigator-initiated studies. His major areas of expertise are clinical trial strategy and trial design and real-world data analysis.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #167: Molecular Genetics of Type 1 Diabetes Part 4

The CTLA4 gene on chromosome 2q33.2 encodes a transmembrane co-receptor expressed on the surface of T cells. This functions as a negative regulator of T-cell activation via interaction with the B7 molecule on antigen-presenting cells (Figure 30.3). The G allele of the +49A/G SNP in exon 1 of CTLA4 has been implicated as a susceptibility marker for T1DM, but was rejected as a causal SNP by a fine-mapping study, which showed that its effect could be explained by more strongly associated variants in a 6.1 kb noncoding region, 3′ of the gene.

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Tim Dunn 2018 Transcript

In this Exclusive Interview transcript, Tim Dunn talks with Diabetes in Control Publisher Steve Freed during the ADA 2018 convention in Orlando about Abbott's research on CGM use and how the FreeStyle Libre system is helping a variety of patients with diabetes.

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