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Daily Archives: Dec 11, 2018

Dec. 11, 2018

We are all very familiar with the onset of type 1 diabetes in young children. In fact, we used to call type one diabetes “juvenile diabetes” until well in to the 1980’s. We no longer use that moniker, but we often think it is the oddity when someone over the …

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PCOS: Motivate Young Women to Make Changes

Young woman, 15 years of age, presented with class II obesity (BMI 37), irregular periods, hirsutism, and continuing to gain weight. Her first visit was with her mother. We met and discussed the possibility of her having polycystic ovarian syndrome because of her symptoms. We confirmed with labs.

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Andrea Dunaif 2018 Complete Interview

Andrea Dunaif, M.D., is the Lillian and Henry M. Stratton Professor of Molecular Medicine and Chief of the J. Lester Gabrilove Division of Endocrinology, Diabetes and Bone Disease at the Icahn School of Medicine at Mount Sinai, New York, NY. Dr. Dunaif is an internationally recognized expert in endocrinology and women’s health. Her research on polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive-age women, has shown that it is a leading risk factor for type 2 diabetes mellitus. Further, this research has revolutionized the treatment of PCOS with insulin sensitizing drugs.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #155: Monogenic Disorders of the Beta Cell Part 5

Neonatal diabetes (NDM) is defined as monogenic beta-cell diabetes which is diagnosed in the first six months of life. It is rare, affecting one in 200,000 live births. The evidence that a diagnosis before 6 months is the cut-off between monogenic neonatal diabetes rather than polygenic T1DM comes from studies of high-risk type 1 HLA, antibodies, birth weight (reduced before 6 months suggests a reduced insulin secretion in utero) and monogenic genetic studies.

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