This week I got a new update from 23 and Me. They had some new data on the effects of gene mutations on major disease and when I looked up diabetes they let me know…based on a few large studies, it is estimated that 30-80% of the risk of developing …

Male, 69 years of age, coronary artery disease,  two cardiac stents, hypertension, hyperlipidemia, prediabetes, bladder cancer.  His sister is 64 years of age, coronary artery disease, prediabetes, PCOS, elevated cardiac calcium score of >1000, no hyperlipidemia. HO early heart disease, stroke, and early death in family. There have been recent reports in the media speaking of the ASPREE Trial, which reported that taking aspirin daily is not effective for all people, and in some it may be more detrimental due to bleeding risks.

Lisa Letourneau, MPH, RD, LDN, is a diabetes researcher, dietitian, and public health professional. As Diabetes and Genetics Clinical Research Manager at the University of Chicago, her work focuses on managing multiple studies related to atypical diabetes, including the largest monogenic diabetes registry in the United States.

In this week's Homerun Slides, we bring you the first question in little game to test your endocrinology knowledge, from a recent presentation by Dr. Claude Lardinois. For (a fictional) $100, this was discovered as part of an evaluation for headaches.

Chronic hyperglycemia as a cause of insulin Resistance: Insulin resistance in patients with type 1 diabetes—a consequence of glucose toxicity? Insulin resistance both precedes and predicts type 2 diabetes and therefore is not merely due to hyperglycemia. In the case of type 1 diabetes, it is clear that insulin resistance is an acquired and reversible phenomenon since insulin sensitivity is completely normalized during remission of the disease.

In this Exclusive Interview transcript, Lisa Letourneau talks with Diabetes in Control publisher Steve Freed during the ADA 2018 convention in Orlando about genetics and diabetes, and how monogenic diabetes differs from type 1 and type 2.

In this Exclusive Interview, Lisa Letourneau talks with Diabetes in Control publisher Steve Freed during the ADA 2018 convention in Orlando about genetics and diabetes.

In part 1 of this Exclusive Interview, Lisa Letourneau talks with Diabetes in Control Publisher Steve Freed about distinguishing monogenic diabetes from other types of diabetes.

In part 2 of this Exclusive Interview, Lisa Letourneau talks with Diabetes in Control Publisher Steve Freed about the genetic diagnosis of monogenic diabetes and determining the proper treatment.

In part 3 of this Exclusive Interview, Lisa Letourneau talks with Diabetes in Control Publisher Steve Freed about the impact of monogenic diabetes on blood sugar levels, which may vary depending on the type of monogenic diabetes diagnosed and other patient-specific factors.