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Daily Archives: Jul 17, 2018

July 17, 2018

Over the years, the fasting glucose has been the standard testing point for diabetes control. However, we have always been proponents of 2-hour postprandial readings to help identify diabetes sooner. This is based on the concept of first phase insulin release, and how that prevents the rise of glucose levels …

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Summer Travel: Don’t Forget the Feet!

Summer, a time for travel for so many. Over the next few weeks, we will look at ways to prevent disasters during or after travel. When it comes to travel plans, a lot of people who have diabetes are most concerned about their medications — getting, bringing enough with them and so many issues associated with that. I've found most aren't concerned about protecting their feet.

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Grenye O’Malley 2018 Complete Interview

Grenye O’Malley, MD, graduated from NYU School of Medicine. She then completed residency in Internal Medicine at the Icahn School of Medicine at Mount Sinai. During residency, she developed an interest in diabetes management and was involved in research on glucose sensor use in patients with type 1 diabetes during pregnancy. She is now a graduating fellow at Icahn School of Medicine at Mount Sinai where she will be an Assistant Professor later this year. She is participating in multiple large clinical trials involving type 1 diabetes technologies, including a closed-loop artificial pancreas study, a first of its kind assessment of decision support algorithms for patients using multiple daily injections, and a study of continuous glucose monitoring in the elderly.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #134: Pathogenesis of Type 2 Diabetes Mellitus Part 5

First-phase insulin secretion: In response to i.v. glucose, insulin is secreted in a biphasic pattern with an early burst of insulin release within the first 10 min followed by a progressively increasing phase of insulin secretion that persists as long as the hyperglycemic stimulus is present. This biphasic insulin response is not observed after oral glucose, because of the more gradual rise in plasma glucose concentration. Loss of first-phase insulin secretion is a characteristic and early abnormality in patients destined to develop T2DM.

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Grenye O’Malley 2018 Transcript

In this Exclusive Interview transcript, Grenye O'Malley talks with Diabetes in Control Publisher Steve Freed during the AACE 2018 convention in Boston, MA about her prenatal diabetes research, the changes that happen for women with type 1 who are pregnant and using insulin pump therapy, and a large multiple trial for the artificial pancreas.

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