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Monthly Archives: August 2017




Aug. 29, 2017

If you put glycocalyx in Google search, you will find a definition that includes “a glycoprotein covering that surrounds the cell membranes of some bacteria, epithelia and other cells.” This does not make much sense when you’re trying to help prevent kidney disease, but this glycoprotein has a lot to do with …

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #88: Measuring Insulin Action In Vivo

Insulin sensitivity based upon the OGTT: The previous discussion suggests that “quick and dirty” indices from fasting values may not be accurate, and it is often true that laboratory procedures are impractical. Recently, it has been suggested that indices calculated from the OGTT may be useful for population studies. For decades the OGTT has been used as a screening test and a diagnostic tool for diabetes and IGT. It might be ideal if one could classify the state of carbohydrate tolerance and simultaneously measure insulin sensitivity and beta-cell function.

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Aug. 26, 2017

It was not uncommon a few years ago to take a patient off metformin when they went on insulin. Metformin was considered a type 2 drug and when someone either had type 1 or they became insulin dependent there was no real value for metformin. I spent 13 years working …

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