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Daily Archives: Jun 7, 2016




Where There’s One Autoimmune Disorder, There May Be Another

Male, 32 years of age, type 1 diabetes, was following gluten free diet of his own choice. Was never diagnosed, just "feels better" when he doesn’t eat gluten. Has lab tests that were negative for celiac in the past. Came to see me for follow up diabetes education. Noted weight loss of 5 pounds in one week. Glucose levels were not elevated, in fact for the most part in target range.

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June 7, 2016

23andMe:  I am sure you have seen the commercials on TV. This is a genetic test that you can get done to learn your ancestry: you simply spit into a tube, mail it away, and presto change-o, all the years of thinking you were from Italy can be erased in a …

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #27: Insulin Gene Expression and Biosynthesis Part 3 of 6

Dysregulation of the insulin gene: There is convincing evidence that abnormalities in insulin gene sequence or function play a role in pancreatic beta-cell dysfunction in type 2 diabetes. Abnormalities in the insulin gene structure consist of rare control region mutations, while insulin gene expression appears to be reduced by metabolic conditions associated with the diabetic state.

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